Search results for "actinia equina"

showing 7 items of 7 documents

Evidence of cytotoxic activity against mammalian red blood cell of Na+ channel neurotoxin (Ae1) from sea anemone (Actinia equina)

2016

The diversification of anthozoan toxins played an important role in the ability to colonize various ecological niches. In this study we evaluated the hemolytic activity of HPLC separated fraction of tentacle extracts of sea anemone Actinia equina. Toxic components from acid tissue tentacle extracts were investigated by size exclusion and reverse phase HPLC to characterize cytolytic molecules. A novel low molecular weight active fraction was sequenced by MALDI TOF analysis and a protein correspondent to 5.4 kDa Sodium channel neurotoxin (Ae1) from A. equina was identified. Synthetic Ae1 was assayed and it showed an hemolytic activity against mammalian erythrocytes in a dose dependent manner.…

0301 basic medicine010405 organic chemistryHemolysinActinia equina; Ae1 neurotoxin; Hemolysin; Na+ channel neurotoxin; Sea anemone; Animal Science and ZoologyAe1 neurotoxinSea anemone01 natural sciences0104 chemical sciencesActinia equina03 medical and health sciences030104 developmental biologylcsh:Biology (General)Na channel neurotoxinNa+ channel neurotoxinAnimal Science and Zoologylcsh:QH301-705.5
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Attività biologica e caratterizzazione molecolare di un peptide neurotossico ad attività litica di Actinia equina (Anthozoa, Cnidaria)

2013

Actinia equina
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Attività citotossica nel muco di Actinia equina (Anthozoa, Cnidaria)

2009

Actinia equinaSettore BIO/05 - Zoologia
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Characterization of cellular and molecular responses of Actinia equina (Linnaeus, 1758)

2014

Actinia equinamolecular responsecellular responses
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The Mucus of Actinia equina (Anthozoa, Cnidaria): An Unexplored Resource for Potential Applicative Purposes

2015

The mucus produced by many marine organisms is a complex mixture of proteins and polysaccharides forming a weak watery gel. It is essential for vital processes including locomotion, navigation, structural support, heterotrophic feeding and defence against a multitude of environmental stresses, predators, parasites, and pathogens. In the present study we focused on mucus produced by a benthic cnidarian, the sea anemone Actinia equina (Linnaeus, 1758) for preventing burial by excess sedimentation and for protection. We investigated some of the physico-chemical properties of this matrix such as viscosity, osmolarity, electrical conductivity, protein, carbohydrate, and total lipid contents. Som…

CnidariaErythrocytesCarbohydratesPharmaceutical ScienceSea anemonePolysaccharideActinia equina; Antibacterial activity; Cytotoxicity; Hemolytic activity; Mucus; Tumor cell line K562; Drug Discovery3003 Pharmaceutical ScienceArticleActinia equinaBiological FactorsCnidarian Venomsantibacterial activityDry weightCell Line TumorAnthozoaDrug DiscoveryAnimalsHumanshemolytic activitylcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)chemistry.chemical_classification<i>Actinia equina</i>tumor cell line K562biologyCytotoxinsHemolytic AgentsEcologyDrug Discovery3003 Pharmaceutical SciencemucuAnthozoabiology.organism_classificationInvertebratesMucusAnti-Bacterial AgentsMucusSea Anemoneslcsh:Biology (General)chemistryBiochemistryMucucytotoxicityRabbitsK562 CellsAntibacterial activityActiniaMarine Drugs
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Isolamento, caratterizzazione e distribuzione cellulare di una neurotossina ad attività litica di Actinia equina (Anthozoa, Cnidaria

2011

actinia equina
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Granulocytes of sea anemone Actinia equina (Linnaeus, 1758) body fluid contain and release cytolysins forming plaques of lysis

2014

The Cnidaria phylum includes organisms that are among the most poisonous animals. The exact composition of cnidarian bioactive molecules is not known in detail, but little is known on the cells that produce the toxins. Here we have shown that the presence of cytolysins is not exclusive of nematocysts. A plaque-forming assay was carried out with cell populations extracted from the percoled body fluid showed for the first time that anthozoan granulocytes are able to form plaque of lysis. We have partitioned the total population of free cells into three distinct discrete bands by discontinuous Percoll gradient, and we have identified six small different types cells: morular granulocytes; cells…

plaque of lysicytolysinActinia equinaplaque of lysisgranulocytelcsh:Biology (General)granulocyteslcsh:QH301-705.5cytolysin; Actinia equina; granulocytes; plaque of lysis; sphingomyelinsphingomyelinInvertebrate Survival Journal
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